A selective

PD 150606 – 5 mg

Brand:
Cayman
CAS:
179528-45-1
Storage:
-20
UN-No:
Non-Hazardous - 2811 / 6.1

The calpains are a family of calcium-dependent cysteine proteases which catalyze limited proteolysis of substrates.{22459} PD 150606 is a selective, cell-permeable inhibitor of calpains (Ki = 0.21 μM for μ-calpain (calpain-1) and 0.37 μM for m-calpain (calpain-2)).{22460} PD 150606 is commonly used to elucidate the roles for calpains in cell function, particularly in how they relate to apoptosis.{22457,22458,22456}  

 

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Description

A selective, cell-permeable inhibitor of calpains (Ki = 0.21 μM for μ-calpain (calpain-1) and 0.37 μM for m-calpain (calpain-2))

Formal name: 3-(4-iodophenyl)-2Z-mercapto-2-propenoic acid

Synonyms: 

Molecular weight: 306.1

CAS: 179528-45-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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