A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders; metabolized to the active compound phosphoramide mustard

Cyclophosphamide (hydrate) – 5 g

Brand:
Cayman
CAS:
6055-19-2
Storage:
-20
UN-No:
Excepted Quantity - 3464 / 6.1

Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders.{21842,21833} In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug since it is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.{22688,20436}  

 

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Description

A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders; metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death

Formal name: N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, monohydrate

Synonyms:  Endoxan

Molecular weight: 279.1

CAS: 6055-19-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|DNA Alkylating Agents||Research Area|Cancer|Cell Death||Research Area|Cancer|DNA Damage and Repair||Research Area|Immunology & Inflammation|Autoimmunity

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