An active metabolite of nitazoxanide; active against M. tuberculosis (MIC = 16 µg/ml); reduces the growth of L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 μM

Tizoxanide – 1 mg

Brand:
Cayman
CAS:
173903-47-4
Storage:
-20
UN-No:
Non-Hazardous - /

Tizoxanide is an active metabolite of the antiparasitic nitazoxanide (Item No. 13692).{17926} Tizoxanide is formed from nitazoxanide via deacetylation of nitazoxanide in the stomach. It is active against M. tuberculosis (MIC = 16 µg/ml). It also reduces the growth of the disease-causing parasites L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM), and inhibits hepatitis B and hepatitis C virus replication (EC50 = 0.15 μM for both).{19983,19984,19985}  

 

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Description

An active metabolite of nitazoxanide; active against M. tuberculosis (MIC = 16 µg/ml); reduces the growth of L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 μM, respectively); inhibits influenza A replication (EC50s = 0.3-1 μM); inhibits hepatitis B and hepatitis C virus replication (EC50 = 0.15 μM for both)

Formal name: 2-hydroxy-N-(5-nitro-2-thiazolyl)-benzamide

Synonyms:  NSC 697856

Molecular weight: 265.3

CAS: 173903-47-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis||Research Area|Infectious Disease|Parasitic Diseases|Chagas Disease||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis||Research Area|Infectious Disease|Viral Diseases|Hepatitis||Research Area|Infectious Disease|Viral Diseases|Influenza||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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