A broadly applicable antiparasitic compound that demonstrates IC50 values of 2.5 and 10 µM for Giardia and Cryptosporidium

Nitazoxanide – 250 mg

Brand:
Cayman
CAS:
55981-09-4
Storage:
-20
UN-No:
Non-Hazardous - /

Nitazoxanide (NTZ) is a broadly applicable antiparasitic compound that is rapidly metabolized to tizaxonide whereupon it enters cells and inhibits pyruvate-ferredoxin oxidoreductase.{17926} NTZ demonstrates IC50 values of 2.5 and 10 µM for Giardia and Cryptosporidium, respectively. Additionally, NTZ kills replicating and nonreplicating M. tuberculosis with an IC50 value of 1 µM, while seemingly evading the development of resistance.{17926}  

 

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Description

A broadly applicable antiparasitic compound that demonstrates IC50 values of 2.5 and 10 µM for Giardia and Cryptosporidium, respectively; kills replicating and nonreplicating M. tuberculosis with an IC50 value of 1 µM, while seemingly evading the development of resistance

Formal name: 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide

Synonyms:  NSC 697855|NTZ

Molecular weight: 307.3

CAS: 55981-09-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis||Research Area|Infectious Disease|Parasitic Diseases|Giardiasis

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