A natural alkaloid in the betel nut; an agonist of the muscarinic acetylcholine receptors M1

Arecoline (hydrobromide) – 250 mg

Brand:
Cayman
CAS:
300-08-3
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Arecoline is a natural alkaloid that is found in the betel nut of the Areca palm. It is an agonist of the muscarinic acetylcholine receptors with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively.{18340,18339,19164} Generally, arecoline causes smooth muscle contraction.{18340,18343,18342} Arecoline and other muscarinic receptor agonists have been shown to improve learning and memory and may prove to be useful in treating dementia.{18345,18341,18344}  

 

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Description

A natural alkaloid in the betel nut; an agonist of the muscarinic acetylcholine receptors M1, M2, M3, M4, and M5; causes smooth muscle contraction; has been shown to improve learning and memory and may prove to be useful in treating dementia

Formal name: 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, monohydrobromide

Synonyms: 

Molecular weight: 236.1

CAS: 300-08-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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