A metabolite of PGE1 with significantly reduced biological activity

13,14-dihydro-15-keto Prostaglandin E1 – 5 mg

Brand:
Cayman
CAS:
5094-14-4
Storage:
-20
UN-No:
Non-Hazardous - 1231 / 3

13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity.{4383,182,2126} Steady state plasma concentrations are about 10 pg/ml.{4383} 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 µM, respectively, compared to PGE1 which has an IC50 of 40 nM.{960}  

 

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Description

A metabolite of PGE1 with significantly reduced biological activity

Formal name: 9,15-dioxo-11α-hydroxy-prostan-1-oic acid

Synonyms:  13,14-dihydro-15-keto PGE1

Molecular weight: 354.5

CAS: 5094-14-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Immunology & Inflammation|Gastric Disease||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways||Research Area|Lipid Biochemistry|Glycerophospholipids|Phosphatidyl Inositol Kinases & Phosphatases||Research Area|Neuroscience|Neuroprotection|Ischemia||Research Area|Neuroscience|Pain Research||Research Area|Neuroscience|Seizure Disorders

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