A potent inhibitor of iNOS (IC50 = 0.20 μM)

N-Benzylacetamidine (hydrobromide) – 100 mg

Brand:
Cayman
CAS:
186545-76-6
Storage:
-20
UN-No:
Non-Hazardous - /

Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.20 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 µM).{17417}  

 

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Description

A potent inhibitor of iNOS (IC50 = 0.20 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 μM)

Formal name: N-(phenylmethyl)-ethanimidamide, monohydrobromide

Synonyms: 

Molecular weight: 229.1

CAS: 186545-76-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Research Area|Cell Biology|Cell Signaling|Nitric Oxide Signaling||Research Area|Immunology & Inflammation

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