A selective inhibitor of Src kinases

SU6656 – 5 mg

Brand:
Cayman
CAS:
330161-87-0
Storage:
-20
UN-No:
Non-Hazardous - /

The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively).{17348} It weakly inhibits some other kinases when used at >10 μM.{17348,14995} SU6656 has been used to study the role of Src kinases in cell growth and development in diverse processes, including nervous system development, fibrosis, and cancer.{17349,17350,17351}  

 

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Description

A selective inhibitor of Src kinases, including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, and 170 nM, respectively)

Formal name: 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

Synonyms: 

Molecular weight: 371.5

CAS: 330161-87-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|SRC Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|SRC Family Signaling

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