A potent inhibitor of PLD

Halopemide – 5 mg

Brand:
Cayman
CAS:
59831-65-1
Storage:
-20
UN-No:
Non-Hazardous - /

Halopemide is a potent inhibitor of phospholipase D (PLD), inhibiting human PLD1 and PLD2 in vitro (IC50 = 220 and 310 nM, respectively) and PLD activity in cells.{16821} Previously, halopemide has been found to inhibit dopamine receptors and was evaluated as a neuroleptic agent.{17063}  

 

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Description

A potent inhibitor of PLD, inhibiting human PLD1 and PLD2 in vitro (IC50 = 220 and 310 nM, respectively) and PLD activity in cells; inhibits the dopamine receptor

Formal name: N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-ethyl]-4-fluoro-benzamide

Synonyms:  NSC 354856|R34301

Molecular weight: 416.9

CAS: 59831-65-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis

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