A platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells

Carboplatin – 250 mg

Brand:
Cayman
CAS:
41575-94-4
Storage:
-20
UN-No:
Non-Hazardous - /

Carboplatin is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. It has cytotoxic effects in ovarian, lung, and other cancer cell lines (IC50s = 14-200 μM).{24628,24627} Carboplatin has been widely studied in clinical settings both alone or in combination with other agents to treat various solid tumors.{24626}  

 

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Description

A platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death; cytotoxic to ovarian, lung, and other cancer cell lines (IC50s = 14-200 μM)

Formal name: (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2-)-κO,κO”]-platinum

Synonyms:  NSC 201345|NSC 241240|Paraplatin®|Ribocarbo-L

Molecular weight: 371.3

CAS: 41575-94-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cancer|Cell Death||Research Area|Cancer|DNA Damage and Repair||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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