15(S)-15-methyl Prostaglandin D2 – 500 µg

Brand:
Cayman
CAS:
85280-90-6
Storage:
-20
UN-No:
- 1231 / 3

15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 (Item No. 12010). In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation.{1139} It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).{1139}  

 

Available on backorder

SKU: 12730 - 500 µg Category:

Description

15(S)-15-methyl PGD2 is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation.{1139} It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).{1139}


Formal name: 9α,15S-dihydroxy-11-oxo-15-methyl-prosta-5Z,13E-dien-1-oic acid

Synonyms:  15(S)-15-methyl PGD2

Molecular weight: 366.5

CAS: 85280-90-6

Purity: ≥95%

Formulation: A solution in methyl acetate


Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypotension||Research Area|Cardiovascular System|Vasculature|Vasoconstriction||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway