BW 245C is a selective agonist for the DP1 receptor.{3128

BW 245C – 1 mg

Brand:
Cayman
CAS:
72814-32-5
Storage:
-20
UN-No:
Non-Hazardous - /

BW 245C is a selective agonist for the DP1 receptor.{3128,711} The Ki of BW 245C for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM.{3128} It has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation{419} and an IC50 of 250 nM for the inhibition of rat platelet aggregation.{711}  

 

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Description

BW 245C is a selective agonist for the DP1 receptor.{3128,711} The Ki of BW 245C for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM.{3128} It has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation{419} and an IC50 of 250 nM for the inhibition of rat platelet aggregation.{711}

Formal name: (4S)-(3-[(3R,S)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxo)-4-imidazolidineheptanoic acid

Synonyms: 

Molecular weight: 368.5

CAS: 72814-32-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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