An α-glucosidase inhibitor that delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase (IC50s = 0.16 and 2.9 µM

Acarbose – 1 g

Brand:
Cayman
CAS:
56180-94-0
Storage:
-20
UN-No:
Non-Hazardous - /

Acarbose is the first identified α-glucosidase inhibitor. It has been shown to delay the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase with IC50 values of 0.16 and 2.9 µM, respectively.{22628,22626} It has also been shown to bind to phosphorylase kinase, potentiating its activity.{31726} In clinical trials, acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.{22629}  

 

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SKU: 11885 - 1 g Category:

Description

An α-glucosidase inhibitor that delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase (IC50s = 0.16 and 2.9 µM, respectively)

Formal name: O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,​5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose

Synonyms:  BAY-g 5421

Molecular weight: 645.6

CAS: 56180-94-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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