An anti-ulcer chalcone derivative; blocks inflammation

Sofalcone – 250 mg

Brand:
Cayman
CAS:
64506-49-6
Storage:
-20
UN-No:
Non-Hazardous - /

Sofalcone is an anti-ulcer chalcone derivative.{21334,21336} It blocks inflammation by suppressing the production of nitric oxide, TNF-α, and MCP-1 while inducing the expression of heme oxygenase-1 when used at 10-20 μM.{21337} Sofalcone (20-50 μM) induces VEGF expression in gastric epithelial cells and promotes gastric ulcer healing following eradication therapy for H. pylori.{21333,21332,21335}  

 

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SKU: 11882 - 250 mg Category:

Description

An anti-ulcer chalcone derivative; blocks inflammation, inducing HO-1 and VEGF expression in gastric epithelial cells; promotes gastric ulcer healing following eradication therapy for H. pylori

Formal name: 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-acetic acid

Synonyms:  Solon|SU 88

Molecular weight: 450.5

CAS: 64506-49-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Immunology & Inflammation|Gastric Disease|Peptic Ulcers||Research Area|Immunology & Inflammation|Innate Immunity

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