Description
A triterpene glycoside; decreases hydrogen peroxide-induced intracellular ROS production and cell death in N2a neuroblastoma cells at 0.4 mg/ml; decreases immobility time in the forced swim and tail suspension tests in mice, indicating anti-depressant like activity, at 50 mg/kg; decreases migration and tube formation in 2H11 and 3B11 cells, as well as HUVECs when used at greater than 15 µM; inhibits the growth of MDA-MB-231, SHG-44, HCT8, A549, and PC3M cancer cells (IC50s = 32.4, 36.9, 40.3, 44.4, and 45.4 µM, respectively)
Formal name: (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl)-4a,6a-methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran-10-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside
Synonyms:
Molecular weight: 929.1
CAS: 382146-66-9
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer||Research Area|Neuroscience|Behavioral Neuroscience|Depression||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen
