An alkaloid with diverse biological activities; reduces lipid peroxidation

Vasicine – 5 mg

Brand:
Cayman
CAS:
6159-55-3
Storage:
-20
UN-No:
Non-Hazardous - /

Vasicine is an alkaloid isolated from A. vasica with diverse biological activities.{36452,36453,36454} In vivo, vasicine (0.2 mg/kg) reduces lipid peroxidation, increases activity of the antioxidases superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) peroxidase (Gpx), and increases levels of GSH in lung in a rat model of toxin-induced asthma.{36452} It reduces ammonia- and capsaicin-induced coughing frequency in mice as well as citric acid-induced coughing frequency in guinea pigs.{36453} Vasicine (5-45 mg/kg) increases phenol red secretion, a marker of expectorant activity, in mice. It also extends pre-convulsive time, a marker of bronchodilation, in guinea pigs. Vasicine also stimulates uterine contractions in rats and mice.{36454}  

 

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SKU: 11760 - 5 mg Category:

Description

An alkaloid with diverse biological activities; reduces lipid peroxidation, increases activity of the antioxidases SOD, CAT, and Gpx, and increases levels of GSH in lung in a rat model of toxin-induced asthma (0.2 mg/kg); reduces coughing frequency in mice and guinea pigs; acts as an expectorant in mice and a bronchodilator in guinea pigs (5-45 mg/kg); stimulates uterine contractions in rats and mice

Formal name: (3S)-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazolin-3-ol

Synonyms: 

Molecular weight: 188.2

CAS: 6159-55-3

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma

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