Description
An inhibitor of the hedgehog signaling pathway (IC50s = 500-700 nM); induces a variety of birth defects in vivo; reduces lipid accumulation and PPARγ and C/EBPα gene expression in 3T3-L1 adipocytes in vitro,
Formal name: (2’R,3S,3’R,3’aS,6’S,6aS,6bS,7’aR,11aS,11bR)-2,3,3’a,4,4’,5’,6,6’,6a,6b,7,7’,7’a,8,11a,11b-hexadecahydro-3-hydroxy-3’,6’,10,11b-tetramethyl-spiro[9H-benzo[a]fluorene-9,2’(3’H)-furo[3,2-b]pyridin]-11(1H)-one
Synonyms: NSC 23898|NSC 7520
Molecular weight: 425.6
CAS: 469-59-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Alkaloids||Research Area|Cell Biology|Cell Signaling|Hedgehog Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity