Description
A natural product and metabolite of curcumin; has anti-inflammatory, antioxidant, and anticancer properties; reduces PMA-induced PGE2 production by 37% in human colonic epithelial cells (20 µM); inhibits LPS-induced overproduction of nitric oxide in RAW 264.7 macrophage cells (3.125-25 µM); inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation (50 µM); prevents formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer
Formal name: 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone
Synonyms:
Molecular weight: 374.4
CAS: 36062-05-2
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cancer||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|iNOS
