A phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM

Bavachin – 1 mg

Brand:
Cayman
CAS:
19879-32-4
Storage:
-20
UN-No:
Non-Hazardous - /

Bavachin is a flavonoid first isolated from seeds of P. corylifolia. It is a phytoestrogen that activates the estrogen receptors ERα and ERβ (EC50s = 320 and 680 nM, respectively).{31782,31780} Through this action, bavachin stimulates osteoblast proliferation and differentiation and prevents bone loss following ovariectomy in rats.{31779,31781} Bavachin less potently inhibits acyl-coenzyme A:cholesterol acyltransferase (IC50 = 86 µM).{31778}  

 

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SKU: 11685 - 1 mg Category:

Description

A phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively); stimulates osteoblast proliferation and differentiation and prevents bone loss following ovariectomy in rats

Formal name: (2S)-2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

Synonyms:  Corylifolin

Molecular weight: 324.4

CAS: 19879-32-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Phytosterols||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Small Molecule Inhibitors|Acyltransferases||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Lipid Biochemistry|Acyl-CoAs||Research Area|Lipid Biochemistry|Sterol Lipids

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