A pentacyclic triterpene; inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells at 10 μM; inhibits IKK-mediated phosphorylation of IκBα in monocytes

α-acetyl Boswellic Acid – 5 mg

Brand:
Cayman
CAS:
89913-60-0
Storage:
-20
UN-No:
Non-Hazardous - /

α-acetyl Boswellic acid is a pentacyclic triterpene and isomer of β-acetyl-boswellic acid (Item No. 11674) originally isolated from B. serrata.{42584} It inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells when used at a concentration of 10 μM.{42584} α-acetyl Boswellic acid also inhibits phosphorylation of IκBα mediated by IκB kinases (IKKs) in monocytes.  

 

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SKU: 11673 - 5 mg Category:

Description

A pentacyclic triterpene; inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells at 10 μM; inhibits IKK-mediated phosphorylation of IκBα in monocytes,

Formal name: (3α,4β)-3-(acetyloxy)-olean-12-en-23-oic acid

Synonyms:  3-O-acetyl-α-Boswellic Acid|ABA|α-Boswellic Acid Acetate

Molecular weight: 498.7

CAS: 89913-60-0

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Immunology & Inflammation|Innate Immunity

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