Description
An amide alkaloid; induces mortality in C. pipiens pallens, A. aegypti, and A. togoi third instar larvae (LC50s =0.86, 0.92, and 0.71 ppm, respectively); cytotoxic to HL-60 and MCF-7 cancer cells (IC50s = 13 and 1.8 µg/ml, respectively); inhibits HMGB1-induced TNF-α, IL-1α, and IL-1β production and ERK1/2 phosphorylation in HUVECs at 10 and 20 µM; prolongs survival time in a HMGB1-induced mouse model of sepsis at 9 µg/animal,
Formal name: (2E,4E)-N-(2-methylpropyl)-2,4-decadienamide
Synonyms:
Molecular weight: 223.4
CAS: 18836-52-7
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Cancer||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Immunology & Inflammation|Innate Immunity|Sepsis/Shock
