A semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM); has applications in breast cancer and hormone-refractory prostate cancer; intended for research applications

Docetaxel – 250 mg

Brand:
Cayman
CAS:
114977-28-5
Storage:
-20
UN-No:
Non-Hazardous - /

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.  

 

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SKU: 11637 - 250 mg Category:

Description

A semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM); has applications in breast cancer and hormone-refractory prostate cancer; intended for research applications

Formal name: (αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, 12b-(acetyloxy)-12-(benzoyloxy)-2aR,3,4S,4aS,5,6R,9S,10,11S,12S,12aR,12bS-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

Synonyms:  NSC 628503|RP 56976|Taxotel

Molecular weight: 807.9

CAS: 114977-28-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Microtubule Dynamics||Research Area|Cancer||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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