Description
An antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes; used as a research tool to disrupt intracellular H+ and K+ concentration, thus altering pH, membrane potential, and cell volume
Formal name: (R)-2-((2R,3S,6R)-6-(((2S,4R,5R,7R,9R,10R)-2-((2S,2’R,3’S,5R,5’R)-5’-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-2,3’-dimethyloctahydro-[2,2’-bifuran]-5-yl)-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)methyl)-3-methyltetrahydro-2H-pyran-2-yl)propanoate, monosodium salt
Synonyms: NSC 292567
Molecular weight: 747
CAS: 28643-80-3
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Toxoplasmosis
