A cell-permeable mycotoxin which binds to the barbed end of actin

Cytochalasin B – 5 mg

Brand:
Cayman
CAS:
14930-96-2
Storage:
-20
UN-No:
De Minimis - 1544 / 6.1

Cytochalasin B is a cell-permeable mycotoxin which binds to the barbed end of actin, reversibly inhibiting the elongation and shortening of actin filaments.{20528} By disrupting actin polymerization, cytochalasin B blocks diverse cellular functions, including cell division, migration, phagocytosis, exocytosis, chemotaxis, and glucose transport.{20527,20526,20524} Cytochalasin B is broadly used in cytological studies involving any of these many processes that depend on actin polymerization.{20525,20530,20529}  

 

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SKU: 11328 - 5 mg Category:

Description

A cell-permeable mycotoxin which binds to the barbed end of actin, reversibly inhibiting the elongation and shortening of actin filaments; blocks diverse cellular functions, including cell division, migration, phagocytosis, exocytosis, chemotaxis, and glucose transport

Formal name: (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione

Synonyms:  NSC 107658|Phomin

Molecular weight: 479.6

CAS: 14930-96-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking

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