An active metabolite of aflatoxin B1; induces hepatocyte hyperplasia and hepatocellular carcinoma tumor formation in rats at 1 mg/kg; increases hepatic total lipid levels and inhibits hepatic mitochondrial and cytoplasmic protein synthesis in rats

Aflatoxin M1 – 100 µg

Brand:
Cayman
CAS:
6795-23-9
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Aflatoxin M1 (AFM1) is an active metabolite of aflatoxin B1 (Item No. 11293).{61120} It induces hepatocyte hyperplasia and hepatocellular carcinoma tumor formation in rats when administered at a dose of 1 mg/animal. AFM1 (6 mg/kg) increases hepatic total lipid levels and inhibits hepatic mitochondrial and cytoplasmic protein synthesis in rats.{61121}  

 

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SKU: 11297 - 100 µg Category:

Description

An active metabolite of aflatoxin B1; induces hepatocyte hyperplasia and hepatocellular carcinoma tumor formation in rats at 1 mg/kg; increases hepatic total lipid levels and inhibits hepatic mitochondrial and cytoplasmic protein synthesis in rats

Formal name: (6aR,9aR)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione

Synonyms:  AFM1

Molecular weight: 328.3

CAS: 6795-23-9

Purity: ≥98%

Formulation: A powder

Product Type|Biochemicals|Toxins|Mycotoxins||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer||Research Area|Toxicology|Cell Health & Viability|Mitochondrial (dys)Function||Research Area|Toxicology|Drug Metabolism|Drug Metabolites||Research Area|Toxicology|Environmental

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