A mycotoxin; induces hepatocellular carcinoma tumor formation and lethality in rats at 1.4 and 3 mg/animal; inhibits various liver and kidney mitochondrial enzymes in rats

Aflatoxin G1 – 1 mg

Brand:
Cayman
CAS:
1165-39-5
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Aflatoxin G1 is a mycotoxin that has been found in A. terricola.{57298} In vivo, aflatoxin G1 is lethal to ducklings (LD50 = 1.18 mg/kg).{57299} It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1 also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase, NADH oxidase, α-glycerophosphate dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase in rats.{57300}  

 

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Description

A mycotoxin; induces hepatocellular carcinoma tumor formation and lethality in rats at 1.4 and 3 mg/animal; inhibits various liver and kidney mitochondrial enzymes in rats

Formal name: (7aR,10aS)-3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3′,2′:4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione

Synonyms: 

Molecular weight: 328.3

CAS: 1165-39-5

Purity: ≥98%

Formulation: A powder

Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Toxicology|Cell Health & Viability|Mitochondrial (dys)Function

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