A divalent cation ionophore

A23187 – 5 mg

Brand:
Cayman
CAS:
52665-69-7
Storage:
-20
UN-No:
Non-Hazardous - /

A23187 is a divalent cation ionophore. While more selective for Mn2+, it is commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways.{20154} A23187 is also used to produce apoptosis through calcium overload, as occurs during hypoxic or oxidative stress.{20153,20152}  

 

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SKU: 11016 - 5 mg Category:

Description

A divalent cation ionophore, commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways; also used to produce apoptosis through calcium overload, as occurs during hypoxic or oxidative stress

Formal name: 5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl-4-benzoxazolecarboxylic acid

Synonyms:  Calcimycin

Molecular weight: 523.6

CAS: 52665-69-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization

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