An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg); binds to tubulin (Ki = 3.4 μM) and prevents tubulin polymerization

CAY10647 – 10 mg

Brand:
Cayman
CAS:
1253697-49-2
Storage:
-20
UN-No:
Non-Hazardous - /

CAY10647 is an aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg).{19224} This compound also binds to tubulin (Ki = 3.4 μM) and prevents tubulin polymerization.{19224}  

 

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SKU: 10791 - 10 mg Category:

Description

An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg); binds to tubulin (Ki = 3.4 μM) and prevents tubulin polymerization

Formal name: (4-fluorophenyl)(2-(4-methoxyphenyl)-1H-imidazol-4-yl)methanone

Synonyms: 

Molecular weight: 296.3

CAS: 1253697-49-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cancer|Multidrug Resistance

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