Description
A purine derivative that reversibly antagonizes aryl hydrocarbon receptor signaling (IC50 = 127 nM in CD34+ cells); induces a 50-fold increase in human embryonic stem cells expressing CD34 (EC50 = 120 nM) and a 17-fold increase in stem cells that retain the ability to engraft immunodeficient mice
Formal name: 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol
Synonyms: SR1
Molecular weight: 429.5
CAS: 1227633-49-9
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cell Biology|Stem Cell Research|Differentiation