A cannabimimetic indole with selectivity for the CB1 receptor (Ki = 29 and 146 nM

JWH 251 – 10 mg

Brand:
Cayman
CAS:
864445-39-6
Storage:
-20
UN-No:
Non-Hazardous - /

JWH 251 is a cannabimimetic indole that shows a high affinity for the central cannabinoid (CB1) receptor with a Ki value of 29 nM and a comparatively modest affinity for the peripheral cannabinoid (CB2) receptor (Ki = 146 nM).{17655} JWH 251 stimulates GTPγS binding of CB1 and CB2 receptors with EC50 values of 29 and 8.3 nM, respectively.{17655}  

 

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SKU: 10578 - 10 mg Category:

Description

A cannabimimetic indole with selectivity for the CB1 receptor (Ki = 29 and 146 nM, for CB1 and CB2, respectively); and comparatively modest affinity the CB2 receptor (Ki = 146 nM); stimulates GTPγS binding of CB1 and CB2 receptors with EC50 values of 29 and 8.3 nM, respectively

Formal name: 2-(2-methylphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone

Synonyms: 

Molecular weight: 319.4

CAS: 864445-39-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Cannabinoids|Synthetic Cannabinoids

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