An HMG-CoA reductase inhibitor (IC50s = 73

Atorvastatin (calcium salt hydrate) – 10 mg

Brand:
Cayman
CAS:
357164-38-6
Storage:
-20
UN-No:
Non-Hazardous - /

Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.{37553} Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.  

 

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SKU: 10493 - 10 mg Category:

Description

An HMG-CoA reductase inhibitor (IC50s = 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively)

Formal name: 2-(4-fluorophenyl)-βR,δR-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, hemicalcium salt, hydrate

Synonyms: 

Molecular weight: 577.7

CAS: 357164-38-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Lipid Biochemistry|Sterol Lipids

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