An endocannabinoid analog specifically designed to be a potent and selective inhibitor of the cellular uptake of AEA; inhibits the cellular uptake of tritiated AEA (IC50 = 3 µM) in RBL-2H3 cells

OMDM-2 – 1 mg

Brand:
Cayman
CAS:
616884-63-0
Storage:
-20
UN-No:
Non-Hazardous - /

Numerous analogs of arachidonoyl ethanolamide{10254} (AEA, anandamide; Item No. 90050) potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty acid amide hydrolase (FAAH) within the neurons.{10647} OMDM-2 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of the cellular uptake of AEA.{11240} Structurally, OMDM-2 is the amide of (R)-tyrosinol with oleic acid. In RBL-2H3 cells, OMDM-2 inhibits the cellular uptake of tritiated AEA with an IC50 of 3 µM, with negligible effects on the CB1 receptor and VR1.{11240}  

 

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SKU: 10179 - 1 mg Category:

Description

An endocannabinoid analog specifically designed to be a potent and selective inhibitor of the cellular uptake of AEA; inhibits the cellular uptake of tritiated AEA (IC50 = 3 µM) in RBL-2H3 cells, with negligible effects on the CB1 receptor and TRPV1

Formal name: (R)-N-(1-(4-hydroxyphenyl)-2-hydroxyethyl)oleamide

Synonyms:  (R)-N-oleoyl Tyrosinol

Molecular weight: 431.7

CAS: 616884-63-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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