A fluorescent probe for highly reactive radicals; upon oxidation by hydroxyl radical

APF – 5 mg

Brand:
Cayman
CAS:
359010-70-1
Storage:
-20
UN-No:
De Minimis - 1231 / 3

APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals.{11242} It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals.{11242} APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively.  

 

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SKU: 10157 - 5 mg Category:

Description

A fluorescent probe for highly reactive radicals; upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals; not oxidized by NO, H2O2 or other oxidants; Fluorescein ex/em = 490/515 nm

Formal name: 2-[6-(4-aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoic acid

Synonyms: 

Molecular weight: 423.4

CAS: 359010-70-1

Purity: ≥98%

Formulation: A solution in methyl acetate

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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