A long-chain N-acylated HSL that functions as a quorum sensing signaling molecule in strains of S. meliloti

N-cis-hexadec-9Z-enoyl-L-Homoserine lactone – 5 mg

Brand:
Cayman
CAS:
479050-94-7
Storage:
-20
UN-No:
Non-Hazardous - /

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} C16:1-Δ9-(L)-HSL is a long-chain AHL that functions as a quorum sensing signaling molecule in strains of S. meliloti.{15835,15834,15833,15828} Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therapy in the treatment of infectious diseases.{15369}  

 

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SKU: 10012673 - 5 mg Category:

Description

A long-chain N-acylated HSL that functions as a quorum sensing signaling molecule in strains of S. meliloti

Formal name: N-[(2S,9Z)-tetrahydro-2-oxo-3-furanyl]-9-hexadecenamide

Synonyms:  C16:1-Δ9-(L)-HSL|N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide

Molecular weight: 337.5

CAS: 479050-94-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Homoserine Lactones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing

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