A long-chain N-acylated HSL that functions as a signaling molecule in the quorum sensing of A. vitis.

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone – 50 mg

Brand:
Cayman
CAS:
1675245-06-3
Storage:
-20
UN-No:
Non-Hazardous - /

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} C14:1-Δ9-cis-(L)-HSL is a long-chain AHL that functions as a signaling molecule in the quorum sensing of A. vitis.{15831} Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therpy in the treatment of infectious diseases.{15369}  

 

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SKU: 10012672 - 50 mg Category:

Description

A long-chain N-acylated HSL that functions as a signaling molecule in the quorum sensing of A. vitis.

Formal name: (S,Z)-N-(2-oxotetrahydrofuran-3-yl)tetradec-9-enamide

Synonyms:  C14:1-Δ9-cis-(L)-HSL|N-(2-oxotetrahydrofuran-3S-yl) Myristoleyl Amide

Molecular weight: 309.4

CAS: 1675245-06-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Homoserine Lactones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing

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