Taprostene (free acid) – 1 mg

Brand:
Cayman
CAS:
108945-35-3
Storage:
-20
UN-No:
Non-Hazardous - /

Taprostene is a stable prostacyclin (PGI2) analog and agonist of the prostacyclin receptor, IP. It does not activate the PGE2 receptor EP4,{15488} which, like IP, promotes vascular smooth muscle relaxation when stimulated. Taprostene has been used extensively to study the role of the IP receptor in tissue preparations{15488,17478} and in vivo.{15995,17479} It has also been used in the screening and evaluation of potential IP antagonists.{15914}  

 

Available on backorder

SKU: 10011348 - 1 mg Category:

Description

A stable prostacyclin analog and agonist of the IP receptor; does not activate EP4


Formal name: 3-[(Z)-[(3aR,4R,5R,6aS)-4-[(1E,3S)-3-cyclohexyl-3-hydroxy-1-propenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-ylidene]methyl]-benzoic acid

Synonyms:  CG 4203|Rheocyclan

Molecular weight: 398.5

CAS: 108945-35-3

Purity: ≥95%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway