An inhibitor of EGF receptor kinase with an IC50 value of 0.8 µM in the human epidermoid carcinoma cell line A431.

AG-183 – 10 mg

Brand:
Cayman
CAS:
122520-90-5
Storage:
-20
UN-No:
Non-Hazardous - /

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation.{14963} AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 0.8 µM in the human epidermoid carcinoma cell line A431.{14963}  

 

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SKU: 10010315 - 10 mg Category:

Description

An inhibitor of EGF receptor kinase with an IC50 value of 0.8 µM in the human epidermoid carcinoma cell line A431.

Formal name: 2-amino-4-(3,4,5-trihydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile

Synonyms:  Tyrphostin 51

Molecular weight: 268.2

CAS: 122520-90-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling

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