An LPA analog containing palmitic acid at the sn-1 position

1-Palmitoyl Lysophosphatidic Acid (sodium salt) – 10 mg

Brand:
Cayman
CAS:
17618-08-5
Storage:
-20
UN-No:
Non-Hazardous - /

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.{15000}  

 

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SKU: 10010290 - 10 mg Category:

Description

An LPA analog containing palmitic acid at the sn-1 position

Formal name: 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt

Synonyms:  1-Palmitoyl LPA

Molecular weight: 432.5

CAS: 17618-08-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Glycerophospholipids||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia||Research Area|Lipid Biochemistry|Glycerophospholipids

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