A competitive NOS inhibitor; more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM)

Methyl-L-NIO (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
150403-96-6
Storage:
-20
UN-No:
Non-Hazardous - /

Nitric oxide synthase (NOS) catalyzes the conversion of L-arginine to nitric oxide (NO) and citrulline. Methyl-L-NIO (hydrochloride) is a competitive nitric oxide synthase (NOS) inhibitor that competes with L-arginine for the amino acid binding site. It is a more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM).{6358}  

 

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SKU: 10010252 - 10 mg Category:

Description

A competitive NOS inhibitor; more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM)

Formal name: N5-(1-iminopropyl)-L-ornithine, monohydrochloride

Synonyms: 

Molecular weight: 223.7

CAS: 150403-96-6

Purity: >98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|eNOS||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|iNOS||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|nNOS

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