A lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester – 10 mg

Brand:
Cayman
CAS:
195503-20-9
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.  

 

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SKU: 10010111 - 10 mg Category:

Description

A lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α

Formal name: 7-[3R,5S-dihydroxy-2R-[3S-hydroxy-5Z-[3-(trifluoromethyl)phenyl]-1R-penten-1E-yl]cyclopentyl]-5-heptenoic acid, methyl ester

Synonyms:  17-trifluoromethylphenyl trinor PGF2α methyl ester

Molecular weight: 470.5

CAS: 195503-20-9

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology

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