A phospholipid; a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques; levels are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma; unilamellar vesicles have been used as substrates to quantify the activity of sPLA2 in the presence or absence of inhibitors; has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions

1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC – 10 mg

Brand:
Cayman
CAS:
35418-59-8
Storage:
-20
UN-No:
De Minimis - 1170 / 3

1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}  

 

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SKU: 10009864 - 10 mg Category:

Description

A phospholipid; a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques; levels are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma; unilamellar vesicles have been used as substrates to quantify the activity of sPLA2 in the presence or absence of inhibitors; has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions

Formal name: 1-ocatadeconyl-2R-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glyceryl-3-phosphorylcholine

Synonyms:  18:0/20:4-PC|1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine|1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine|PC(18:0/20:4)|SAPC

Molecular weight: 810.1

CAS: 35418-59-8

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Cancer||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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