An azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant

SOTS-1 (technical grade) – 5 mg

Brand:
Cayman
CAS:
223507-96-8
Storage:
-80
UN-No:
Non-Hazardous - /

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature.{14956,14957} This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo.  

 

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SKU: 10009642 - 5 mg Category:

Description

An azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate; follows first order kinetics, and exhibits a half-life of 4,900 seconds at physiological pH and temperature

Formal name: 4,4’-[azobis(oxymethylene]bis-benzoic acid

Synonyms:  Di-(4-Carboxybenzyl)Hyponitrite|Superoxide Thermal Source

Molecular weight: 330.3

CAS: 223507-96-8

Purity: ≥80%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Free Radical Generators||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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