(S)-SLV 319 – 1 mg

Brand:
Cayman
CAS:
464213-10-3
Storage:
-20
UN-No:
Non-Hazardous - /

Central cannabinoid (CB1) receptor antagonists may have potential in the treatment of a number of diseases such as neuro-inflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction, and gastrointestinal disorders.{14382} (S)-SLV 319 is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2), respectively.{14382} (S)-SLV 319 is less lipophilic (log P = 5.1) and therefore more water soluble than other known CB1 receptor ligands.{14381}  

 

Available on backorder

SKU: 10009022 - 1 mg Category:

Description

A potent and selective CB1 receptor antagonist (Kis = 7.8 and 7,943 nM for CB1 and CB2, respectively); less lipophilic (log P = 5.1) and therefore more water soluble than other known CB1 receptor ligands


Formal name: 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N’-methyl-4S-phenyl-1H-pyrazole-1-carboximidamide

Synonyms:  BMS 646256|Ibipinabant|JD 5001

Molecular weight: 487.4

CAS: 464213-10-3

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors