A precursor of ceramide and sphingosine; can emulate S1P in cell signaling or have opposite intracellular effects

Sphinganine (d18:0) – 5 mg

Brand:
Cayman
CAS:
764-22-7
Storage:
-20
UN-No:
Non-Hazardous - /

Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins,{18298,18299} as well as in some cancers.{18300} Sphinganine can block protein kinase C activation in some cases but not others.{18301,15200} Sphinganine-1-phosphate can emulate sphingosine-1-phosphate in cell signaling or have opposite intracellular effects.{18297,18302,18303}  

 

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SKU: 10007945 - 5 mg Category:

Description

A precursor of ceramide and sphingosine; can emulate S1P in cell signaling or have opposite intracellular effects,

Formal name: 2S-amino-1,3R-octadecanediol

Synonyms:  D-erythro-Dihydrosphingosine|D-erythro-Sphinganine|Dihydro-D-erythro Sphingosine|Dihydrosphingosine|Sphinganine

Molecular weight: 301.5

CAS: 764-22-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cell Biology|Cell Signaling||Research Area|Lipid Biochemistry|Sphingolipids

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