α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.{9177} The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.{14208} α-CEHC was only excreted when a threshold concentration of 7-9 µmol α-tocopherol/g total lipid in plasma was exceeded. Therefore

α-CEHC – 25 mg

Brand:
Cayman
CAS:
4072-32-6
Storage:
-20
UN-No:
Non-Hazardous - /

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ).{3679} α-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation.{14207} α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.{9177} The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.{14208} α-CEHC was only excreted when a threshold concentration of 7-9 µmol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.{14209}  

 

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SKU: 10007705 - 25 mg Category:

Description

α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.{9177} The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.{14208} α-CEHC was only excreted when a threshold concentration of 7-9 µmol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.{14209}

Formal name: 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-propanoic acid

Synonyms: 

Molecular weight: 278.3

CAS: 4072-32-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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