Description
L-Biopterin is the oxidized form of BH4, a NOS cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs).{15034} L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.{15033}
Formal name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone
Synonyms: L-erythro-Biopterin|NSC 339699
Molecular weight: 237.2
CAS: 22150-76-1
Purity: >98%
Formulation: A crystalline solid
Product Type|Biochemicals||Research Area
