An analog of AEA that binds to the human CB1 receptor with a Ki value of 60 nM; inhibits rat glial gap junction cell-cell communication at a concentration of 50 µM

Arachidonoyl-N-methyl amide – 5 mg

Brand:
Cayman
CAS:
156910-29-1
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of anandamide that binds to the human central cannabinoid (CB1) receptor with a Ki of 60 nM.{9580} It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 µM.{8122}  

 

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SKU: 10007294 - 5 mg Category:

Description

An analog of AEA that binds to the human CB1 receptor with a Ki value of 60 nM; inhibits rat glial gap junction cell-cell communication at a concentration of 50 µM

Formal name: N-methyl-5Z,8Z,11Z,14Z-eicosatetraenamide

Synonyms: 

Molecular weight: 317.5

CAS: 156910-29-1

Purity: >98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Fatty Amides||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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