13,14-dihydro-15-keto Prostaglandin D2 MaxSpec® Standard – 100 µg

Brand:
Cayman
CAS:
59894-07-4
Storage:
-80
UN-No:
De Minimis - 1231 / 3

13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Item Nos. 12010 | 10007202) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor.{5248} It also inhibits ion flux in a canine colonic mucosa preparation.{9769} In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine.{418,35} 13,14-dihydro-15-keto PGD2 MaxSpec® standard is a quantitative grade standard of 13,14-dihydro-15-keto PGD2 (Item No. 12610) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 13,14-dihydro-15-keto PGD2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

Available on backorder

SKU: 10007208 - 100 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,


Formal name: 9α-hydroxy-11,15-dioxo-prost-5Z-en-1-oic acid

Synonyms:  13,14-dihydro-15-keto PGD2

Molecular weight: 352.5

CAS: 59894-07-4

Purity: >95%

Formulation: A solution in methyl acetate at 100 µg/ml


Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway