Description
Thioester analogs of glycerophospholipids, in combination with Ellman’s reagent, are convenient colorimetric substrates for the measurement of phospholipase activity. HEPC is a truncated analog of phosphatidylcholine with the entire sn-1 substituent deleted, and with a hexadecylthioester in the sn-2 position.{12915} HEPC is a substrate for Type II PLA2 enzymes, such as porcine pancreatic, bee venom, and snake venom PLA2. The intrinsic biological activity of HEPC has not been actively investigated.
Formal name: 4-oxide-4-hydroxy-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-thia-4-phosphatetracosan-1-aminium, inner salt
Synonyms: 2-Hexadecanoylthio-1-Ethylphosphorylcholine
Molecular weight: 481.7
CAS: 60793-01-3
Purity: ≥95%
Formulation: A solution in ethanol
Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases