Description
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play”. It has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 value of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of PLA2 activity from a variety of sources.{14107}
Formal name: 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine
Synonyms: Dehydroabietylamine
Molecular weight: 285.5
CAS: 1446-61-3
Purity: ≥98%
Formulation: A solution in ethanol
Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Receptor Pharmacology||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Endocrinology & Metabolism||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors
